Cd69 Gene

CD69 cancer-related Sun S Hu Z Huang S et al. CD69 Gene Is Differentially Regulated in T and B Cells by Evolutionarily Conserved Promoter-Distal Elements1 Berta N.

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CD69 molecule SourceHGNC SymbolAccHGNC1694 Organism.

Cd69 gene. Atlas Genet Cytogenet Oncol Haematol. View mouse Cd69 Chr6129267324-129275375 with. The gene view histogram is a graphical view of mutations across CD69.

Cd69 MGI Mouse Gene Detail - MGI88343 - CD69 antigen. Vazquez Teresa Laguna Juan Carabana Michael S. CD69 molecule HGNC Symbol Chromosome.

Chromosomal mapping placed the mouse CD69 gene on the long arm of chromosome 6 near the NK gene complex that contains the related NKR-P1 and Ly-49 gene families. REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression. CD69 CD69 molecule Authors.

CD69 GEO Profiles NCBI Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus GEO repository. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest or by using the sliders in the filters panel to the left. Cd69 CD69 antigen house mouse CD69 deficiency promotes a prothrombotic phenotype characterized by increased von Willebrand factor and worse brain damage after ischemic stroke.

CD69 and CD25 expression was significantly upregulated on T cells in 11 of 17 and 10 of 17 patients respectively. Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumors Cancer-Prone Deep Insight Case Reports Journals Portal Teaching. Phenotypes sequences polymorphisms proteins references function.

CD69 is induced by integrin alpha4beta1 outside-in signalling and T-cell receptor signalling. Here we provide new insights on the transcriptional regulation of CD69 gene in mammal species. CD69 is important to the suppressive function of Tregs by promoting IL-10 production.

These mutations are displayed at the amino acid level across the full length of the gene by default. The human CD69 gene mapped to chromosome 12p13 near the related NKG2 gene cluster and in a region associated with rearrangements in approximately 10 of cases of childhood acute lymphocytic leukemia. CD69 CD69 Molecule is a Protein Coding gene.

Intron I acts as an important regulatory element of CD69 expression. CD69 overexpression is associated with the human T-cell leukemia virus type 1 infection and adult T-cell leukemia. Binding sites for several inducible transcriptional factors such as nuclear factor NF-κB erythroblast transformation-specific related gene-1 ERG-1 and activator protein- AP- 1 are located within the CD69 gene promoter 3 4.

CD69 expression in hematopoietic lineage undergoes rapid changes depending on the cell-lineage the activation state or the localization of the cell where it is expressed suggesting a complex and tightly controlled regulation. Diseases associated with CD69 include Coccidioidomycosis and Eosinophilic Pneumonia. Chromosome location bp 9752486 -.

CD69 also known as activation inducer molecule very early activation antigen MLR-3 and Leu-23 is a member of the natural killer NK cell gene complex family of signal transducing receptors. Synonyms aim bl-acp26 clec2c ea1 gp3228 mlr-3. CD69 is as a type II transmembrane glycoprotein with a C-type lectin.

Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Kit receptor signaling pathway. The results suggest that CD69 acts as a downregulator of endothelial activation. A combination of CD45RACD45RO and CD45RO identified 11 of 16 infected patients.

CD69 HGNC Symbol Synonyms. Krangel and Pilar. The CD69 gene is located in the natural killer NK gene cluster chromosome 6 in mouse and 12 in human 1 2.

ENSG00000110848 Tissue enhanced bone marrow lymphoid tissue MIM i. Upregulation of CD69 on NK cells was the most sensitive marker for neonatal sepsis sensitivity 81. 72 rows CD molecules CD C-type lectin domain family CLEC Name.

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